PREVALENCE OF HEPATITIS G VIRUS EXPOSURE IN BLOOD DONORS
PREVALENCE OF HEPATITIS G VIRUS EXPOSURE IN BLOOD DONORS
نویسندگان: بهروز نقیلی حکم آبادی , منوچهر خوشباطن
کلمات کلیدی: Keyword(s): HEPATITIS G VIRUS (HGV), BLOOD DONOR, HEPATITIS B VIRUS CO-INFECTION
نشریه: , 37 , 12 , 2007
| نویسنده ثبت کننده مقاله |
بهروز نقیلی حکم آبادی |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
دانشکده پزشکی |
| کد مقاله |
58418 |
| عنوان فارسی مقاله |
PREVALENCE OF HEPATITIS G VIRUS EXPOSURE IN BLOOD DONORS |
| عنوان لاتین مقاله |
PREVALENCE OF HEPATITIS G VIRUS EXPOSURE IN BLOOD DONORS |
| ناشر |
12 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
خیر |
| عنوان نشریه (خارج از لیست فوق) |
|
| نوع مقاله |
سایر موارد |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح چهار – سایر سایت های تخصصی |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
http://majalleh.tbzmed.ac.ir |
| Abstract:
Background and objective: Frequency of Hepatitis G virus exposure in blood donors varies between 2.5% in Japan to 24.2% in Poland. Therefore there is a geographic difference in distribution of Hepatitis G virus (HGV) in the world. We aimed to determine the frequency of HGV exposure in Iranian blood donors.
Material and methods: Blood samples from 478 Iranian volunteer blood donors were tested. Positive anti-E2 samples were tested for HGV RNA by RT PCR using primers derived from the NS5A region of the viral genome.
Results: From 478 donors enrolled in our study, 5(1%) of them were positive for anti-E2. Co-infection of HGV with hepatitis B virus (HBV) was seen in 33.3% but we didn't find HGV and HCV co-infection in our subjects. HGV RNA wasn't observed in 5 anti-E2 positive subjects. We didn't find HGV viremia and antibody at the same time.
Conclusion: Regarding to low frequency of HGV exposure in blood donors it doesn't seem that supervision and screening of blood donors will be necessary. We didn't observe co-infection of HGV with HCV in our subjects, supporting that although parenteral route is the most effective way, other routes such as sexual contact and intra familial contact may also play role in HGV transmission |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| PREVALENCE OF HEPATITIS G VIRUS EXPOSURE IN BLOOD DONORS.docx | 1395/05/03 | 15414 | دانلود |