| خلاصه مقاله | Background:
To evaluate our experience with 35 patients with sacrococcygeal teratoma (SCT) in our hospital over a period of 10 years between 2004 and 2014 and determine the outcome of the management and recommendations for treatment strategies.
Patients and methods:
A retrospective study was conducted at our Pediatric Surgical Unit, Tabriz Children Hospital. The medical records were reviewed for age at presentation, clinical manifestations and investigations, time of surgical approach, histopathology, recurrences, bladder and anorectal function, and cosmetic outcome.
Results:
Thirty-five patients with SCT were referred to the Pediatric Surgical Unit. The time of referral was as follows: immediately after birth in the case of ten patients; during the first week for 17 patients (one of them died before surgery because of hemodynamic instability and other associated congenital anomalies and was excluded from the study); later in infancy for 22 patients; and at one and half years of age for one child. The lesion was excised in the case of 34 patients. Teratomas were of type I (n=5), type II (n=15), type III (n=12), and type IV (n=2) (Altman’s classification). The age of patients at surgery ranged from 2 days to 1.5 years. Histological analysis of results revealed mature teratoma (n=24), immature teratoma (n=7), and malignant teratoma (n=3). The coccyx wasn't removed in three cases during the early period of the study. The follow-up period ranged from 3 months to 10 years. Recurrence occurred in five (12%) cases, wound infection in four (9.7%), and diarrhea in two (4.8%) cases. The a-fetoprotein level was high in 30 cases and was normal in 4 patients; it decreased after excision. Fetal diagnosis was made in 12 cases by means of a prenatal sonographic scan.
Conclusions:
Prenatal diagnosis of SCT is very important and it is recommended to save the baby from obstructed labor. Early diagnosis allows early surgical intervention and avoids malignant transformation. The coccyx should be excised to decrease the risk of recurrence. Skin flap modification is feasible for large teratomas with healthy skin. |