Serological ELISA Test (IgM & IgG) for Prospective Study of Cytomegalovirus (CMV) Infection in Pregnant Women
Serological ELISA Test (IgM & IgG) for Prospective Study of Cytomegalovirus (CMV) Infection in Pregnant Women
نویسندگان: ابوالفضل پورحسن مرزرود
کلمات کلیدی: Keywords: Cytomegalovirus, Congenital Disorders, Maternal- infection, Iran
نشریه: , 3 , 38 , 2009
| نویسنده ثبت کننده مقاله |
ابوالفضل پورحسن مرزرود |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
دانشکده پزشکی |
| کد مقاله |
58123 |
| عنوان فارسی مقاله |
Serological ELISA Test (IgM & IgG) for Prospective Study of Cytomegalovirus (CMV) Infection in Pregnant Women |
| عنوان لاتین مقاله |
Serological ELISA Test (IgM & IgG) for Prospective Study of Cytomegalovirus (CMV) Infection in Pregnant Women |
| ناشر |
6 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
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| عنوان نشریه (خارج از لیست فوق) |
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| نوع مقاله |
Short Communication |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
Iranian Journal of Public Health website |
| Background: Cytomegalovirus (CMV) infection is associated with significant maternal and fetal consequences. The aim of
present study was to determine the current prenatal CMV seroprevalence in Eastern Azerbaijan and evaluate the routine
laboratory diagnostic techniques of anti-CMV immunoglobulin M (IgM) and immunoglobulin G (IgG).
Methods: During the present prospective cross-sectional study, 125 women referred to No. 1 Laboratory of Specialized
Clinics of Tabriz University of Medical Sciences and seeking prenatal care were evaluated during 2003-2006. CMV IgG
and IgM antibodies were determined with ELISA technique. Statistical analyses were performed using the SPSS statistical
package version 13.0.
Results: Eight four percent of the subjects were seropositive. Out of 20 subjects with primary seronegativity, 12 (9.6%) remind
seronegative during reexaminations and follow up, but eight (6.4%) subjects showed primary infection in the second
to third trimesters of gestation. In two (1.6%) of these eight subjects, IgM was persisted for more than 20 months.
Conclusion: Results showed a similar seroprevalence of CMV in Eastern Azerbaijan. Also, we found that ELISA IgM test
was not an appropriate method for differentiation of past or recent CMV infections especially in the pregnant women. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| Serological ELISA Test (IgM & IgG) for Prospective Study of Cytomegalovirus (CMV) Infection in Pregnant Women.pdf | 1395/03/26 | 41967 | دانلود |