| Toxoplasma gondii causes the most common parasitic
infection in the world. Congenital transmission,
prenatal mortality and abortion are major
problems of T. gondii. Prevalence of toxoplasmosis
is high in Iran, especially in Azerbaijan. The current
literature reviewed in this paper reveal results
pertaining to various regions of Iran. The present
cross-sectional e-study was designed to evaluate
the seroprevalence of toxoplasmosis in childbearing
women in Northwest Iran. We evaluated 1659
women in childbearing age from several cities in
Northwestern Iran (Tabriz, Maragheh, Ahar,
Marand, Sarab, Miane) from July 2009 to August
2010. Women aged between 20 and 40 years and
seeking prenatal care were enrolled in the study.
The subjects’ sera were probed with indirect fluorescent
antibody (IFA).
A total of 1659 subjects were examined. Titres
ranged from 1:100 to 1:800. In all, 899 subjects
(54.13%) were seropositive. The highest frequency
of seropositivity was shown in 1:200 dilution
(36.08%) and in subjects from Maragheh (84% of
211 subjects). There was a direct linear relationship
between seropositivity and age (p<0.001). Also,
seroprevalence of toxoplasmosis was higher in
subjects with primary school/lower educational
level (p<0.001) and subjects living in rural regions
(p<0.001).
Overall, more than 50% of women in childbearing
age were seropositive for toxoplasmosis in northwestern
Iran. Increasing seroprevalence of toxoplasmosis
with age was a predictable result due to
longer exposure to the parasite. The relationship
between increasing seroprevalence and lower educational
level as well as living in rural areas is in
line with the latest epidemiological findings,
which also show such relationships due to lower
socioeconomic status. |