مطالعه بیماران هیاتیت cمزمن و شیوع Viremia بین افراد خانوادگی آنها

The Study of Chronic Hepatitis C Patients and the Prevalence of Viremia among Their First-Degree Relatives by the Tabriz University of Medical Sciences


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صفحه نخست سامانه
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دانشگاه علوم پزشکی تبریز
دانشگاه علوم پزشکی تبریز

نویسندگان: محمد پورحسن مقدم , ناصر صمدی , علیرضا نورآذریان , سید منوچهر نورآذریان

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نشریه: 55020 , 16 , 8 , 2014

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نویسنده ثبت کننده مقاله علیرضا نورآذریان
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه دانشکده پزشکی
کد مقاله 57829
عنوان فارسی مقاله مطالعه بیماران هیاتیت cمزمن و شیوع Viremia بین افراد خانوادگی آنها
عنوان لاتین مقاله The Study of Chronic Hepatitis C Patients and the Prevalence of Viremia among Their First-Degree Relatives by the Tabriz University of Medical Sciences
ناشر 4
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ خیر
عنوان نشریه (خارج از لیست فوق)
نوع مقاله Original Article
نحوه ایندکس شدن مقاله ایندکس شده سطح یک – ISI - Web of Science
آدرس لینک مقاله/ همایش در شبکه اینترنت http://www.aensiweb.com/journals.html

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The first-degree relatives of the infected HCV patients do not have sufficient knowledge of this disease, the risks and dangers involved in contracting HVC, nor do they understand what the precautionary measures required to prevent the transmission of this disease. Therefore, it is necessary to study the levels of viremia in these individuals by RT-PCR to determine whether these persons have contracted the disease. Methods: In a recent study on chronic hepatitis and their first-degree relatives by the Tabriz University of Medical Sciences 2138 patients diagnosed with chronic hepatitis along with their first-degree relatives were referred to the university’s clinic for further study and examination, the study began in 2011 and is currently in process (2014). Upon completion of their orientation patients entering the study completed questionnaires, which included demographic variables and the patient’s medical records. The following chemical analyses were preformed; liver function test, white blood cells count (WBC), hematocrit, haptoglobin, albumin, Zn, HBsAg, Anti HBs, HBe Ag, Anti HBc and Anti HCV tests as well as HCV-RNA study by RT-PCR method. Results: Serological test results of the 430 cases of first-degree relatives of the patients diagnosed with hepatitis C, 71 individuals (16.51%) were HCV positive, of which 11 individuals (15.49%) showed markers for HCV-RNA. In this study it was established that there is no significant association between hepatitis C and HIV prevalence in first-degree relatives (P <0.61).Conclusion: Study finding revealed a high prevalence of the viral infection hepatitis C within the community, it is therefore essential for laboratory analyses on all first-degree relatives as well as all persons, exposed to the infected patient. Additionally, due to the high chance of chronic infection, it is imperative to examine the presence of viremia in all cases of positive (HCV-Ab) test results. These results may aid in discovery of the possible sources of infections, the method of transmissions and ultimately, to control and prevention further infection.

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نویسنده نفر چندم مقاله
محمد پورحسن مقدماول
ناصر صمدیدوم
علیرضا نورآذریانسوم
سید منوچهر نورآذریانچهارم

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