چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | ماندانا رفیعی |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | بیماری های گوارش و کبد |
| کد مقاله | 57725 |
| عنوان فارسی مقاله | Association of 5՛-Untranslated Region Polymorphism of VEGF Gene with Henoch-Schönlein in North West of Iran |
| عنوان لاتین مقاله | Association of 5՛-Untranslated Region Polymorphism of VEGF Gene with Henoch-Schönlein in North West of Iran |
| ناشر | 5 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ | خیر |
| عنوان نشریه (خارج از لیست فوق) | Molecular and Biochemical Diagnosis (MBD) |
| نوع مقاله | Original Article |
| نحوه ایندکس شدن مقاله | ایندکس نشده |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | http://mbd.modares.ac.ir/article_13067_d1e7135a6c1451ab0f1b31517abf7241.pdf |
| Background: Henoch-Schönlein purpura (HSP) is an lgA mediated small vessel systemic vasculitis disease in children. The etiology and pathogenesis of HSP disease remain unknown. However, environmental and genetic risk factors could play important roles in susceptibility to HSP disease. In this study we investigated the association of 5՛-untranslated region polymorphism (-634G/C) of VEGF gene with HSP among Iranian Azeri Turkish population. Methods: Thirty unrelated Iranian Azeri Turkish children with HSP and fifty healthy unrelated subjects without HSP and other inflammatory diseases were enrolled in this population. -634G/C polymorphism of VEGF gene was genotyped by polymerase chain reaction–restriction fragment length polymorphism (PCR–RFLP) technique. Results: The distribution of CC genotype in VEGF -634G/C polymorphism statistically showed a significant difference in HSP patients in compare to that of control group (P= 0.009). Conclusions: The CC genotype of VEGF -634G/C polymorphism could be associated with susceptibility to HSP disease in Iranian Azeri Turkish ethnic group. |
| نویسنده | نفر چندم مقاله |
|---|---|
| مهناز صادقی شبستری | سوم |
| ماندانا رفیعی | چهارم |
| فخرالسادات مرتضوی | پنجم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| MOLDIA130671404156600.pdf | 1395/02/09 | 244851 | دانلود |
