چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | علیرضا نورآذریان |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | دانشکده پزشکی |
| کد مقاله | 57521 |
| عنوان فارسی مقاله | بررسی رابطه بین سطوح سرمی هموسیستئین، پروفایل های لیپیدی و استرس اکسیداتیو در خانمهای مبتلا به پراکلامپسی |
| عنوان لاتین مقاله | Investigate The Effects Of Folic Acid Supplementation On Homocysteine Levels In Women With Preeclampsia |
| ناشر | 4 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ | خیر |
| عنوان نشریه (خارج از لیست فوق) | |
| نوع مقاله | Original Article |
| نحوه ایندکس شدن مقاله | ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | http://www.sauerlaender-verlag.com/index.php?id=1376 |
| Pre-eclampsia is a syndrome which is characterized by the increase in blood pressure above 140/90, oedema and proteinuria, and is one of the leading causes of maternal death and of complications in pregnancy that can occur in the second half of pregnancy.Approximately 20 % of pregnant women in developing countries and 5 % of pregnant women worldwide are affected, and it is the second leading cause of maternal death in developing countries, including Iran . Homocysteine (2-amino-4-mercapto-butyric acid), is a sulphur-containing amino acid without special codon and is created by an essential amino acid methionine demethylation from the diet. Homocysteine has sulphydryl group, which makes it more susceptible to other thiol oxidation and disulphide formation. Folic acid is water-soluble vitamin, and despite the need to get pregnancy to avoid disruption process of the nervous system of the fetus, NTD for antioxidant effects reduces oxidative stress, and the concentration and oxidation of homocysteine, therefore, diet and supplements during pregnancy is important.This case-control study was conducted on healthy pregnant women visiting Taleghani and Al Zahra hospitals in Tabriz, Iran, as well as on women with pre-eclampsia admitted to these two hospitals. Fifty-eight samples were selected as controls and 58 subjects were selected as cases. The blood samples were prepared with their consents. Parameter measured included homocysteine concentration in blood. In addition, a questionnaire was completed to collect information on age, gestational stage, height, weight, weight before pregnancy and folic acid (B9) intake. The results in this study are based on the inhibition of confounding variables and indicate significant differences in homocysteine status. The people, who received folic acid supplements during pregnancy were 20, and finally 60% of them were diagnosed with gestational hypertension, have been hospitalized, and 40% of them were in the control group.Elevated homocysteine levels can be considered as a factor in the etiology of preeclampsia. The type of diet and dietary antioxidants, including folic acid, in reducing homocysteine-induced oxidative stress, and improve preeclamptic women is important. |
| نویسنده | نفر چندم مقاله |
|---|---|
| علیرضا نورآذریان | دوم |
| منیژه سیاح ملی | سوم |
| عبدالرسول صفائیان | چهارم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| nourazarian.pdf | 1394/12/26 | 651663 | دانلود |
| nourazarian.pdf | 1394/12/27 | 651663 | دانلود |
