Randomized double-blind study of the effect of dexamethasone and methylprednisolone pulse in the control of rheumatoid arthritis flare-up: a preliminary study
Randomized double-blind study of the effect of dexamethasone and methylprednisolone pulse in the control of rheumatoid arthritis flare-up: a preliminary study
نویسندگان: سوسن کلاهی , علیرضا خبازی اسکویی , وحیده صدرا , مهرزاد حاج علیلوی بناب , مرتضی قوجازاده
کلمات کلیدی: Key words: dexamethasone, methylprednisolone, pulse therapy, rheumatoid arthritis
نشریه: , 1 , , 2015
| نویسنده ثبت کننده مقاله |
سوسن کلاهی |
| مرحله جاری مقاله |
مقالات چاپ شده سامانه قبلی |
| دانشکده/مرکز مربوطه |
دانشگاه علوم پزشکی تبریز |
| کد مقاله |
56832 |
| عنوان فارسی مقاله |
Randomized double-blind study of the effect of dexamethasone and methylprednisolone pulse in the control of rheumatoid arthritis flare-up: a preliminary study |
| عنوان لاتین مقاله |
Randomized double-blind study of the effect of dexamethasone and methylprednisolone pulse in the control of rheumatoid arthritis flare-up: a preliminary study |
| ناشر |
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| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
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| عنوان نشریه (خارج از لیست فوق) |
International Journal of Rheumatic Diseases 2014 |
| نوع مقاله |
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| نحوه ایندکس شدن مقاله |
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| آدرس لینک مقاله/ همایش در شبکه اینترنت |
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| Aim: The objective of this study was to compare the efficacy and safety of dexamethasone and methylprednisolone
for pulse therapy of rheumatoid arthritis flare-up.
Methods: This randomized double-blind controlled study was performed in the Emam Reza Educational Hospital
of Tabriz University of Medical Sciences, Tabriz, Iran. Thirty rheumatoid arthritis patients who had severely
active disease were recruited to the dexamethasone and methylprednisolone pulse groups. Disease activity of all
the patients was measured by the Disease Activity Score in 28 joints (DAS28) at baseline, and days 4 and 30.
Results: The differences in the DAS28 at days 4 and 30, and the number of patients whose DAS28 obtained less
than 3.2 and 2.6 in the dexamethasone and methylprednisolone groups were non-significant. There was not any
significant difference between the adverse effects of the treatments in the two groups.
Conclusions: The results of the study suggest that dexamethasone pulse therapy is a safe and effective treatment
for severe rheumatoid arthritis flare-up |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| rib~56832~1445503021~pulseA.pdf | 1394/7/30 | 127994 | دانلود |