Elevated levels of interleukin-23 in sera of patients with pemphigus vulgaris
Elevated levels of interleukin-23 in sera of patients with pemphigus vulgaris
نویسندگان: فرزانه پاکدل , فیروز پور علی بابا , زهره بابالو , تهمورث عبدالهیان , سولماز پور زارع مهربانی
کلمات کلیدی:
نشریه: 16554 , 4 , 9 , 2012
| نویسنده ثبت کننده مقاله |
فرزانه پاکدل |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
دانشگاه علوم پزشکی تبریز |
| کد مقاله |
43602 |
| عنوان فارسی مقاله |
Elevated levels of interleukin-23 in sera of patients with pemphigus vulgaris |
| عنوان لاتین مقاله |
Elevated levels of interleukin-23 in sera of patients with pemphigus vulgaris |
| ناشر |
5 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
بلی |
| عنوان نشریه (خارج از لیست فوق) |
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| نوع مقاله |
Original Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
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| BACKGROUND:
Pemphigus vulgaris, a chronic mucocutaneous disease, is the most prevalent type of pemphigus which manifests with development of bullae and erosions on skin and mucosal membranes.
OBJECTIVES:
To investigate the potential role of IL-23 in pemphigus vulgaris.
METHODS:
In this study, 30 patients with pemphigus vulgaris and 30 healthy individuals were selected according to inclusion and exclusion criteria. Measurement of IL-23 serum levels in blood samples was conducted by ELISA. Data was analyzed using Student's t-test for comparison of IL-23 levels between the two groups.
RESULTS:
Mean serum levels of IL-23 in patients with pemphigus and healthy controls were 25.1 ± 4.2 and 17.9 ± 4.7 pg/ml, respectively (p<0.05).
CONCLUSIONS:
Based on the findings of this study, serum levels of IL-23 were higher in patients with pemphigus in comparison to healthy individuals with no clinical significance. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |